Lipid nanostructures for antioxidant delivery: a comparative preformulation study

• Elisabetta Esposito,
• Maddalena Sguizzato,
• Markus Drechsler,
• Paolo Mariani,
• Federica Carducci,
• Claudio Nastruzzi,
• Giuseppe Valacchi and
• Rita Cortesi

Beilstein J. Nanotechnol. 2019, 10, 1789–1801, doi:10.3762/bjnano.10.174

• lipid carriers (NLCs); retinoic acid; skin pollution; solid lipid nanoparticles (SLNs); Introduction Air pollution increasingly affects industrialized urban areas in a negative manner with dramatic consequences for the environment and human health. This problem also affects rural areas, worsening the

• formulation screening appears imperative [35][36]. The present investigation has been conducted to develop a nanoparticulate approach for counteracting skin pollution. In particular, a preformulation study was performed to select the type and composition of lipid nanoparticles suitable for encapsulation of